The halothane hepatitis that was not
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چکیده
منابع مشابه
That was the week that was.
As the Royal College of Nursing Congress drew to a close in Harrogate members were in no doubt their national pay campaign had gathered momentum. It was no longer just about a 3 per cent pay rise for every nurse in the country, but about the future of the NHS itself.
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Geriatric medicine has an encyclopaedic sweep, reflecting the complexity of both the ageing process and of our patient group. Keeping up with, and making sense of, the relevant scientific literature is challenging, especially as ageing has increased in prominence as a focus of research across many branches of the sciences and the humanities. This review of research published in 2012 in generali...
متن کاملThe molecular basis of halothane-induced hepatitis.
Halothane hepatitis The anaesthetic agent halothane (CF,CHCIRr) causes two distinct types of liver damage. About 20% of halothane-exposed patients exhibit mild hepatotoxicity, characterized by transient elevations in liver enzymes. In contrast, a much smaller fraction of patients exposed to halothane (between 1 in 3500 and 1 in 35 000) develop severe hepatotoxicity, commonly termed ‘halothane h...
متن کاملHalothane macrophage migration inhibtiion factor test in halothane-associated hepatitis.
As an index of delayed hypersensitivity in vitro halothane macrophage migration inhibition factor tests (halothane-MIF tests) were performed on peripheral blood lymphocytes from five patients with halothane hepatitis. Twenty-two subjects exposed to halothane, but with no evidence of jaundice, five 'healthy' hospital anaesthetists, nine jaundiced subjects without halothane exposure, and 10 healt...
متن کاملHalothane hepatitis in a young child.
A 4-year-old girl developed severe hepatitis following the fourth administration of halothane in a period of 5 months. She was shown to have a circulating antibody which acted specifically against rabbit hepatocyte previously sensitized to halothane. The patient made a full recovery from the hepatitis, but 5 months later, developed diabetes mellitus.
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2020
ISSN: 0007-0912
DOI: 10.1016/j.bja.2019.09.018